How long can you live with Stage 4 cholangiocarcinoma?
Many studies report a dismal median survival of approximately 6 months. In this case, we have a patient diagnosed with cholangiocarcinoma who has remarkably exceeded life expectancy to greater than 4 years with a fourth line agent Sorafenib.
What is death from cholangiocarcinoma like?
Approximately half of untreated patients die within 3–4 months of presentation from the indirect effects of local tumor progression, bile duct obstruction, liver failure or sepsis from cholangitis and abscesses.
Can hepatic resection provide a long term cure for patients with intrahepatic cholangiocarcinoma?
Results: The median, 1-year, 3-year, and 5-year disease-free survival was 10 months, 44%, 18%, and 11%, respectively; the corresponding overall survival was 27 months, 75%, 37%, and 22%, respectively. The probability of being cured of ICC was 9.7% (95% confidence interval, 6.1%-13.4%).
Can surgery cure cholangiocarcinoma?
Surgical resection is the only potentially curative treatment for patients with cholangiocarcinoma. For both perihilar cholangiocarcinoma (pCCA) and intrahepatic cholangiocarcinoma (iCCA), 5‐year overall survival of about 30% has been reported in large series.
Does anyone survive cholangiocarcinoma?
The 5-year survival rate for extrahepatic bile duct cancer is 10%. If the cancer is diagnosed in an early stage, the 5-year survival rate is 17%. If the cancer has spread to the regional lymph nodes, the 5-year survival rate is 16%.
Does Chemo work for cholangiocarcinoma?
If you have bile duct cancer that has spread, you may receive chemotherapy as the main treatment if surgery is not an option. Research has suggested that the combination of gemcitabine and cisplatin can lengthen the lives of people with bile duct cancer that cannot be removed by surgery.
What is cholangiocarcinoma stage4?
Stage IV: In stage IV intrahepatic bile duct cancer, cancer has spread to other parts of the body, such as the bone, lungs, distant lymph nodes, or tissue lining the wall of the abdomen and most organs in the abdomen.
Is cholangiocarcinoma slow growing?
Cholangiocarcinomas are usually slow-growing tumors that spread locally via the lymphatic system. Treatment and long-term prognosis are dependent upon the location of the mass.
How do you beat cholangiocarcinoma?
Treatments for cholangiocarcinoma (bile duct cancer) may include:
- Surgery. When possible, surgeons try to remove as much of the cancer as they can.
- Liver transplant.
- Chemotherapy.
- Radiation therapy.
- Targeted drug therapy.
- Immunotherapy.
- Heating cancer cells.
- Photodynamic therapy.
What is cholangiocarcinoma prognosis?
The outlook (prognosis) for people with cholangiocarcinoma is usually poor. The five-year survival rate for bile duct cancer that hasn’t spread outside of the bile ducts is 10% to 15%. This rate drops to 2% if the cancer spreads to areas of the body that are far from the bile ducts, such as the lungs.
What is the best treatment for cholangiocarcinoma?
Treatments for cholangiocarcinoma (bile duct cancer) may include:
- Surgery. When possible, surgeons try to remove as much of the cancer as they can.
- Liver transplant.
- Chemotherapy.
- Radiation therapy.
- Targeted drug therapy.
- Immunotherapy.
- Heating cancer cells.
- Photodynamic therapy.